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Tran Manh Hung profile

Interim Dean of Biomedical Science Department

Short personal statement

Affiliations:
Pharmaceutical Biology Lab, Biomedical Science Department, School of Life Science, VNUK
Phone:
+84-97-214-8084
Email:
hung.tran@vnuk.edu.vn
  • Education
    • PhD in Pharmaceutical Science, College of Pharmacy, Chungnam National University, Korea, 2008
    • MS in Pharmaceutical Science, College of Pharmacy, Chungnam National University, Korea, 2005
    • BS in Biotechnology, Hanoi Open University, Vietnam, 2002
  • Experience
    • Research Professor, Lecturer (Sep, 2012~Dec, 2015), Division of Pharmacognosy, Natural Products Chemistry Lab, College of Pharmacy, Catholic University of Daegu, Korea
    • Lecturer, Researcher (Jan 2011~Sep, 2012); Faculty of Chemistry, University of Sciences, Ho Chi Minh National University, Vietnam
    • Visiting Scientist (Feb, 2010 ~ Jan, 2011), Department of Medicinal Resources, Institute of Natural Medicine, University of Toyama, Japan
    • Postdoctoral Researcher (Feb, 2009 ~ Feb, 2010), Pharmacognosy and Natural Products Chemistry Lab, College of Pharmacy, Catholic University of Daegu, Korea
    • Postdoctoral Researcher (Feb, 2008 ~ Feb, 2009), Bio-therapeutic Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Korea
  • Research Interests
    • Medicinal herbs, Pharmacognosy/Vietnamese Traditional Medicines (VTM), Phytochemistry, Phytotherapy, Pharmacology, Biochemistry, Natural products analysis/Standardization; Sustainable use of herbal drug resources
    • Biological activity and Pharmaceutical applications: Anti-cancer, Anti-inflammation Alzheimer’s disease, Ant-diabetics; Atherosclerosis; Ant-oxidant
  • Research Projects
    • “Study on the anti-pancretic cancer by natural medicinal plants collected from the central land of Vietnam”. Vietnam Ministry of Education, 2017-2019, Code YD-001; Tran Manh Hung, Vietnam
    • “Study on the cytotoxic and anti-tumor activities of active compounds from Vietnamese traditional medicinal plant, Caesalpinia sappan” This research is funded by Vietnam National Foundation for Science and Technology Development (NAFOSTED) under grant number 106.05-2011.52; 2011-2014; Tran Manh Hung, Vietnam
    • “Study on the sassaine diterpene alkaloids constituents from Erythrophleum fordii and their anti-angiogenic effect”; This research was supported by the National Research Foundation of Korea Grant funded by the Korean Government (MEST) (KRF-2012R1A2A06046921 and KRF-2012R1A1A2003547); 2012-2013; Byung Sun Min, Korea
    • “Anti-amnesic effect of alkaloid fraction from Lycopodiella cernua (L.) Pic. Serm. on scopolamine-induced memory impairment in mice”; This research is funded by Vietnam National Foundation for Science and Technology Development (NAFOSTED) under grant number 104.99-2011.19; 2011-2014; Tran Cong Luan; Vietnam
    • “Anti-cancer effect of active compounds from Ganoderma lucidum”; This research was supported by a grant from the National Research Foundation of Korea funded by the Korean government (no. NRF-2009-0084675); Byung Sun Min. Daegu Catholic University, Korea
    • “Studies on the Identification of the Efficacy of Biologically Active Components from Oriental Herbal Medicines”; This study was supported by the Ministry of Knowledge Economy in 2008 (Chungnam TP, Grant) and the National Research Foundation of Korea Grant funded by the Korean Government (MEST) (NRF-C1ABA001-2010-0020484); Byung Sun Min; Korea
    • “Studies on the Identification of the Efficacy of Biologically Active Components from Oriental Herbal Medicines”; This research was supported by Korea Research Foundation Grant (KRF-2007-331-E00331); KiHwan Bae; Korea
  • Selected Publications
    • Hoang LS, Hung TM, Lee JS, Ngo TTM, Woo MH, Min BS. Inflammatory inhibitory activity of sesquiterpenoids from Atractylodes macrocephala Rhizomes. Chemical & Pharmaceutical Bulletin, 64(5), 507-511 (2016).
    • Ha MT, Hung TM, Kim JA, Jo KY, Kim J, Kim WD, Cheon WJ, Woo MH, Ryu SH, Min BS. Potential pancreatic lipase inhibitory activity of phenolic constituents from the root bark of Morus alba L. Bioorganic & Medicinal Chemistry Letters, 26(12), 2788-94 (2016).
    • Nguyen HX, Nguyen NT, Nguyen MH, Le TH, Van Do TN, Hung TM*, Nguyen MT. Tyrosinase inhibitory activity of flavonoids from Artocarpus heterophyllous. Chemistry Central Journal, 2016 Jan 29;10:2. doi: 10.1186/s13065-016-0150-7. eCollection 2016.
    • Hung TM,* NTT Mai, NH Dang, NT Dat, PT Thuong. Cytotoxic constituents from the seeds of Vietnamese Caesalpinia sappan. Pharmaceutical Biology, 53(10), 1549-1554 (2015).
    • Hung TM, Lee JS, Chuong NN, Kim JA, Oh SH, Woo MH, Choi JS, Min BS. Kinetics and molecular docking studies of cholinesterase inhibitors derived from water layer of Lycopodiella cernua (L.) Pic. Serm. (II). Chemico-Biological Reactions, 240, 74-82 (2015).
    • Hung TM,* NTT Mai, NH Dang, NT Dat, PT Thuong. Cytotoxic constituents from the seeds of Vietnamese Caesalpinia sappan. Pharmaceutical Biology, 53(10), 1549-1554 (2015).
    • TH Do, TL Le, TM Hung,* VNH Le, MK Nguyen, VD Le, BS Min, ND Nguyen. An improved HPLC-DAD method with quantitative comparisons of Ganoderma lucidum and its five related species originated from Vietnam. Molecules, 20(1), 1059-1077 (2015).
    • NN Chuong, Huong NTT, TM Hung,* Luan TC. Anti-cholinesterase activity of Lycopodium alkaloids from Vietnamese Huperzia squarrosa (Forst.) Trevis. Molecules 19(11), 19172-19179 (2014).
    • TM Hung, TD Cuong, Kim JA, Lee JH, Woo MH, Min BS. In vitro apoptotic effect of cassaine-type diterpene amides from Erythrophleum fordii on PC-3 prostate cancer cells. Bioorganic & Medicinal Chemistry Letters 24(21), 4989-4994 (2014).
    • NN Chuong, BH Trung, TC Luan, TM Hung, NH Dang, NT Dat. Anti-amnesic effect of alkaloid fraction from Lycopodiella cernua (L.) Pic. Serm. on scopolamine-induced memory impairment in mice. Neuroscience Letters 575, 42-46 (2014).
    • TM Hung*, NH Dang, NT Dat. Methanol extract from Vietnamese Caesalpinia sappan induces apoptosis in HeLa cells. Biological Research 47(1), 20 (2014).
    • TM Hung, TD Cuong, JA Kim, N Tae, JH Lee, BS Min Cassaine diterpene alkaloids from Erythrophleum fordii and their anti-angiogenic effect. Bioorganic & Medicinal Chemistry Letters 24(1), 168-172 (2014).
    • TM Hung,* NX Hai, NT Nhan, TT Quang, TL Quan, TD Cuong, NH Dang, NT Dat. Cytotoxic activity of new phenolic compounds from Vietnamese Caesalpinia sappan. Bioscience, Biotechnology, and Biochemistry 77(12), 2378-2382 (2013).
    • Youn UJ, Fatima N, Chen QC, Chae S, Hung TM, Min BS. Apoptosis-inducing and antitumor activity of neolignans isolated from Magnolia officinalis in HeLa cancer cells. Phytotherapy Research 27(9), 1419-1422 (2013).
    • Cuong TD, Hung TM, Kim JC, Kim EH, Woo MH, Choi JS, Lee JH, Min BS. Phenolic compounds from Caesalpinia sappan heartwood and their anti-inflammatory activity. Journal of Natural Products 75(12), 2069-2075 (2012).
    • TM Hung,* TC Luan, BT Vinh, TD Cuong, BS Min. Labdane-type diterpenoids from Leonurus heterophyllus and their cholinesterase inhibitory activity. Phytotherapy Research 25(4), 611—614 (2011).
    • MK Lee, TM Hung, TD Cuong, Na M, Kim JC, Kim EJ, Park HS, Choi JS, Lee I, Bae K, Hattori M, BS Min. Ergosta-7,22-diene-2β,3α,9α-triol from the fruit bodies of Ganoderma lucidum induces apoptosis in human myelocytic HL-60 cells. Phytotherapy Research 25(11), 1579—1585 (2011).
    • TM Hung,* NH Dang, TD Cuong, S Zhu, PQ Long, K Komatsu, BS Min. Flavonoid glycosides from Chromolaena odorata leaves and their In vitro cytotoxic activity. Chemical & Pharmaceutical Bulletin, 59(1), 129—131 (2011).
    • Full publication, please see: https://www.researchgate.net/profile/Hung_Tran_Manh
  • Invited lectures
    • Innovative ideas in natural medicine research: perspective views. Invited lecture, Toyama International Conference Center, Toyama city, February 18-19, 2010, Japan.
    • Anti-cancer effects of active ingredients from -Linh Chi- Ganoderma lucidum. Invited lecture. Apply Science and Technology Conference, Duy Tan University, Danang city, November 14-15, 2012, Vietnam.
    • Vietnamese medicinal plants as potential anticancer agents. Invited lecture. International Symposium for the Extension of Multi-purpose Natural Products, St. Damian Hall, Catholic University of Daegu, Kyeongbuk city, October 28, 2014, Korea.
    • Study on the anti-Alzheimer diseases from Vietnamese medicinal plants, Invited lecture. Ton Duc Thang University, Hochiminh city, January 24, 2015, Vietnam.
    • Screening of AChE inhibitors from Vietnamese Lycopodium sp. and understanding their molecular mechanism to combat Alzheimer’s disease. Invited lecture. Green Pharmacy Symposium, The 12th Scientific conference celebrating the 55th anniversary of Vietnam National Institute of Medicinal Materials. Hanoi April 13, 2016.
  • Patent
    • ANTI-CANCER COMPOSITION COMPRISING ERGOSTA-7,22-DIEN-3[beta],5[alpha],6[alpha]-TRIOL (PAT – KR20110088637). SUN MOK INST EDUCATION FOUNDATION. Republic of Korea 2010.

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